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Consequently, these models may not fully replicate the clinical progression observed in human patients

Non-irradiated bacteria, used as control, showed a curved or spiral shape and their bacterial surface appeared intact, with one or a few flagella at one end (Figure 6A)

Pivotal support for this strategy comes from the phase III KEYNOTE-522 trial in early-stage TNBC, in which neoadjuvant pembrolizumab combined with platinum-based chemotherapy significantly increased pathological complete response (pCR) rates and event-free survival compared with chemotherapy alone [55]
