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Research shows that administering PPs to KKAY mice on a HFD effectively reduces weight gain and lowers plasma insulin, TG, LDL-C, and blood glucose levels while increasing HDL-C and liver glycogen

Can J Neurol Sci 44:9095 Izecka J (2003) Total antioxidant status is increased in the serum of amyotrophic lateral sclerosis patients

doi: 10.1155/2019/6175804 38 SametJMWagesPA

Moreover, silibinin mitigates immunosuppression and inhibits tumor progression by limiting PD-L1 protein expression in lung cancer (A549, H292, and H460), papillary thyroid cancer (TPC-1), and nasopharyngeal carcinoma (C666-1) cells [889, 892, 897]
