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PMID: 28699143 4 Organic anion transporters in remote sensing and organ crosstalk
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This dual action rescues energy-deprived neurons and shifts microglia from destructive M1 to reparative M2 phenotypes

In disease-causing TNFRSF1A variants, the autophagy system is defective leading to apoptosis and elevated production of mitochondrial-derived reactive oxygen species (ROS) (42)
