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Furthermore, populations that permanently live at high altitude have genetic adaptations that cause a blunted HIF-1 response 144
Thiem H, Folkerts H, Vlkel L
Yazbeck VY, Georgakis GV, Li Y, McConkey D, Andreeff M , Younes A
Its derived from a naturally occurring protein found in human stomach (gastric) juice, which is part of the reason researchers first became interested in it the body already produces a version of this compound as part of its natural protective processes
