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Retrieved 26 July 2016

Collagen and Extracellular Matrix Remodeling Much of the dermatologic interest in GHK-Cu stems from its role in the extracellular matrix (ECM)

Notably, several uremic solutes have also been implicated in systemic endothelial dysfunction and microvascular injury, suggesting a link to the proteinuriarelated cerebrovascular changes observed in epidemiological PD studies [145]

It is a bidirectional communication network involving the vagus nerve, the enteric nervous system, the immune system, and metabolic signaling pathways that physically connect intestinal health to brain function
