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Augmentation of lipid metabolism was observed in a study by Varady et al
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Additionally, cocaine use in PLWH upregulates expression of activated leukocyte cell adhesion molecule in brain endothelium, promoting monocyte adhesion and transmigration across the BBB (131)
In many studies, ROS-induced apoptosis is linked to cytochrome C release and caspase-3/9 9 (CASP3/9) activation [86,87,88]
