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On Days 15 and 30, mice in the Niacin 2 group exhibited a significant higher weight gain compared to the Control group

Structurally, GCH1 is organized into a homodecameric formation, comprising two pentameric rings aligned into a toroidal configuration, with each monomer possessing a catalytic domain essential for the activity of GCH1 (184)

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10.1074/jbc.M110.119958 127 MiyauchiA.DinavahiR