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Description
Their results showed that TSA pretreatment downregulated histone deacetylase 1 (HDAC1) expression, thereby promoting nuclear translocation of Nrf2 and upregulating antioxidant proteins, including HO-1, cystine transporter xCT and GSH peroxidase 4 (Gpx4)

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Like Hashimotos disease, its considered an autoimmune condition

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