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Obesity is characterized by a decrease in anti-inflammatory/atheroprotective adipokines and an increase in proinflammatory/atherogenic adipokines (139)

Biomarkers for endothelial function, insulin sensitivity, intracellular signaling, maintaining DNA integrity , inflammation, metabolic flexibility, mitophagy (recycling old and damaged mitochondria) and cellular senescence (also called "zombie cells" as these cells have lost proper function, harm nearby cells and do not die off) are all improved

However, when the patent expires, other manufacturers can produce its generic version

The formation and activation of the PANoptosome within a single cell also support PANoptosis