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Epithelial MLCK-dependent barrier dysfunction mediates T-cell activation-induced diarrhea in vivo Cytoskeletal contraction due to myosin II (regulatory)-light chain (MLC) phosphorylation is necessary for barrier disruption and in vitro inhibition of myosin light chain kinase (MLCK) restores barrier function following cytokine treatment

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Probiotic Lactobacillus plantarum promotes intestinal barrier function by strengthening the epithelium and modulating gut microbiota

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doi: 10.1080/19490976.2021.1907272

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10.1056/NEJMOA1413687 29 GaliN.GhofraniH

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