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MAO-A and -B oxidize DA into 3,4-dihydroxyphenlacetaldehyde (DOPAL), which is oxidized by ALDH to 3,4-dihydroxyphenylacetic acid (DOPAC), or reduced by aldehyde reductase (ARL) to 3,4-htdroxyphenylglycol (DHPG)

However, they may experience ratio compression from interfering peptides, potentially underestimating true protein abundance fold changes

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