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The uncontrolled generation of GSSG during oxidative stress can contribute to mitochondrial dysfunction by glutathionylation of target proteins, as described below

This large muscle is easily identified on the upper, outer thigh making it a safe injection site for self-administration

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SCOPE OF REVIEW This review summarizes key functions of GSH and focuses on factors that regulate the biosynthesis of GSH, including pathological conditions where GSH synthesis is dysregulated