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Allergic diseases are associated with reduced blood levels of ascorbic acid, or vitamin C, a necessary antioxidant that prevents excessive oxidative stress and inflammation without reducing the defensive capacity of the immune system

Article PubMed PubMed Central Google Scholar He, H

doi: 10.1271/bbb.110320

Likewise, multifunctional nanomedicine platforms designed to induce ferroptosis, such as DHA-loaded Fe 3+ -doped MnO 2 nanosheets, may trigger excessive ROS generation and glutathione depletion beyond the tumor boundary, potentially leading to systemic inflammation, immune dysfunction, and off-target toxicity that could compromise patient safety