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Phosphorylated STAT proteins dimerize and translocate to the nucleus, where they bind to DNA and initiate the transcription of target genes involved in inflammation, immune regulation, and cellular growth [67]

Efficacy and safety of modafinil for treatment of amphetamine-type stimulant use disorder: a systematic review and meta-analysis of randomized placebo-controlled trials: Efficacit et innocuit du modafinil pour le traitement des troubles lis lusage de stimulants de type amphtamine : revue systmatique et mta-analyse dessais randomiss contrls par placebo

ROS are also critical to triggering the cytoprotective pathway Keap1/Nrf2
