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elegans glutathione cytosol O-GlcNAcylation of SKN-1 modulates the lifespan and oxidative stress resistance in Caenorhabditis C. elegans retrograde response. The
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Specifically, it upregulates genes involved in collagen synthesis (Types I, III, and V), decorin production (which regulates collagen fibril assembly), integrin and glycosaminoglycan synthesis, DNA repair enzymes, antioxidant defense systems (superoxide dismutase, glutathione), and stem cell markers
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10.1021/acs.jafc.7b02125 271
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