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Medication Adjustments If side effects remain problematic despite conservative measures, discuss with your physician options such as temporarily reducing the dose, extending time at current dose before escalating, or switching to the oral formulation which may have a different tolerability profile for some patients

Since equal amounts of all three polypeptide chains are needed to produce fibrinogen, when synthesis of one of the chain of fibrinogen is suppressed, it will have a general inhibitory effect on fibrinogen synthesis [44]

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