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Molecules , 2020 Irritable Bowel Syndrome (IBS) IBS is marked by abnormal gut motility, inflammation, and hypersensitivity
doi: 10.1093/ajcn/nqac246
Insulin resistance results in increased estrogen levelsboth by increasing aromatase activity, resulting in the conversion of testosterone into estrogen, and by decreasing sex-hormone-binding globulin, resulting in greater amounts of free circulating estrogen.[2] Insulin resistance also causes increased production of inflammatory mediators, which likely contributes to estrogen-sensitive conditions including fibroids
Immunity 30 (1), 8091
