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In BRAF V600 -mutant melanoma, PD-L2 is upregulated in CD11c + immunocytes by intrinsic methylation, instigating the loss of T cell-mediated inflammation and gain of BRAF inhibitor tolerance
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doi: 10.1016/0304-4165(85)90182-5
Recognizing these stages early can help prevent long-term nerve damage and serious complications
