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Du JH, Zhou MT, Chen Q, Tao YC, Ren J, Zhang Y, Qin HL

To quote from a very comprehensive review, which deals with that subject precisely: Addiction is more likely and more severe in individuals who take drugs via rapid routes of drug delivery
R., Elizondo Luvano, J

However, treatment with antimicrobial combinations had significant concerns on patient outcomes and antimicrobial stewardship, observational studies conducted in the past decade indicated that combination of two or more antimicrobial agents as a treatment of MDR infections had better patient outcomes in comparison with monotherapy, at least in critically ill patients, as stated by an international cross-sectional survey performed by ESCMID in large hospitals
