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Description
2010;23:S194S198
It is known to elicit its toxic effects by enhanced production of ROS which adversely impact all the major cellular biomolecules: lipids, proteins and DNA
This lends support to the notion that the main physiological roles of these enzymes is in regulating the concentrations of lipid peroxides that are poorly or not metabolized by catalase or APX, or in peroxide sensing
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