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Elevated secretion of the cytokines TNF-, IL-6, and IL-1 is associated with elevated neuronal inflammation, which is accompanied by decreased expression of anti-inflammatory mediators including IL-10 (9)

10.1038/jidsymp.2008.3 11 BolkeL.SchlippeG.GerJ.VossW

In species that already possess the thiol- or RuMP-linked pathways, the THF-dependent pathway for methyl transfer may still act as a secondary or auxiliary system for the removal of formaldehyde
