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In PCOS, estrogen receptors and the balance between estrogen and progesterone become abnormal, resulting in estrogen dominance

Journal of Cellular Physiology, 232(10), 27312740

Overall, the levels of BiP/Grp78 and the occurrence of pPERK in AD neurons correlate well with the presence of abnormally phosphorylated Tau and Braak staging of NFTs (133)

P = 0.07)
