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The metabolism of BHB in heart or brain leads to the formation of mitochondrial acetyl CoA and citrate [60, 61]
Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses

Therefore, small-molecule inhibitors of the Munc13-4STX7 interaction are hypothesized to reduce inflammation by limiting overactivation of TLR7-dependent and TLR9-dependent pathways

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