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These findings indicate that butyrate administration modulates the composition of the intestinal flora, promoting the presence of beneficial Lactobacillus while reducing the abundance of harmful Enterococcus , consistent with the results reported by Li X

However, SCFAs are also copiously produced from many other nutrients, including proteins and fructose 15,34 , and excessive SCFAs can contribute to hepatic lipogenesis and worsen metabolic disorders through the gutbrain axis 15,35

piR-39980 promotes cell proliferation, migration and invasion, and inhibits apoptosis via repression of SERPINB1 in human osteosarcoma

Apr 2021;46(2):295-303