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This helped prevent bruising and swelling, which would have been much more likely had she injected directly into the fragile under-eye skin

Polyphenols can prevent ototoxicity of cisplatin by improving cellular antioxidant homeostasis, modulating signaling pathways, mitigating inflammatory responses, and ameliorating the disruption of cisplatins intra-auricular environment in a dose- and time-dependent manner (Maiuolo et al., 2022).Moreover, after studies of natural compounds with anti-tumor properties, polyphenols have emerged as strong chemotherapeutic sensitization candidates (Jakobui Brala et al., 2023

PLOS One 14 , e0224941 (2019)

however, registration and listing failures were also noted in one warning letter following a 704(a)(4) request and in five inspection-based letters