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Maffulli N, Cuozzo F, Migliorini F, Oliva F
ONOO- inhibits Na-alanine co-transport ( ASCT1 ) by reducing its affinity for alanine and Na-glutamine co-transport ( B0AT1 ) by decreasing co-transporter numbers, revealing potential mediation of NaAAcT alterations in inflammation (152)
Figure 2A depicts a group of TH-positive cells that are negative for neuromelanin
It was proposed that these transporters play a key role maintaining the glutamate gradient between brain cells and extracellular fluid, since they are the most important players because they catalyze Glu efflux from the brain
