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instead, it can selectively protect specific phosphates containing two PUFA acyl chains from oxidative degradation, thereby inhibiting ferroptosis

NCT03125902 (2024) A study of Atezolizumab and Paclitaxel versus placebo and Paclitaxel in participants with previously untreated locally advanced or metastatic triple negative breast cancer (TNBC) (IMpassion131)

Therefore, across the bone marrow, liver, and spleen, the failure of specialized ECs to maintain mitochondrial health appears to be a conserved mechanism leading to the local collapse of tissue-specific architecture and regenerative capacity

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