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By selectively interfering with the FOXO4-p53 interaction, FOXO4-DRI has become a compound of interest in research models focused on senescent cell biology and age-associated cellular processes
Cells were treated with two well known depleting agents, diethyl maleate (DEM) and buthionine sulfoximine (BSO), and the cellular and nuclear glutathione levels were assessed by analytical and confocal microscopic techniques, respectively
