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AMPK is the main energy sensor that regulates the dynamic balance of ATP/AMP levels up-regulated and phosphorylated by APS (Zou et al., 2009

Viral hijack of hACE2 in the BBB axis could impair autonomic nervous system (ANS) and dysregulate blood pressure and respiration 76

PMC6739475 Wiley / Food Frontiers Updated review on NMN and NR mechanisms: NAD+-SIRT1-PGC-1 axis, PARP-1 hyperactivation, and neurodegeneration (peer-reviewed, 2024/2025) PMC / NIH Nicotinamide mononucleotide research in cardiovascular biology