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Steroids (2012) 77(4):30611

Thus, microglia not only produce inflammatory mediators that enter the bloodstream through pro-inflammatory signaling by CORT but also activate their apoptotic pathways, leading to programmed cell death after sustained immune activity
Arch Biochem Biophys 323:429437 Quijano C, Alvarez B, Gatti RM, Augusto O, Radi R (1997) Pathways of peroxynitrite oxidation of thiol groups

However, routine treatment can make a difference if necessary and is part of a well-rounded and comprehensive health plan