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Several clinical studies have demonstrated decreased levels of BDNF in bipolar depressed and manic patients (215)

doi: 10.1016/j.tplants.2008.04.003

In this same animal model, knocking out the FGF21 gene leads to exacerbation of the intoxicating effects of ethanol

Furthermore, cells incubated with 100 M -EC, GSH, or UDE containing 100 M -EC demonstrated significantly lower levels of LPS-induced IL-1 (Fig
