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Just as we use a discount rate on future cash flows to figure out retirement, were doing the same thing on physiologic parameters

Neurology 62, 812819

Laboratory research has documented interactions with vascular endothelial growth factor (VEGF) and related growth factors involved in angiogenesis, the formation of new blood vessels, making this a significant area of interest in regenerative research

That can mean more frequent colds, longer recovery times, recurring infections, and even an increased susceptibility to inflammatory or autoimmune conditions
