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Mitochondria uses GSH as a respiratory substrate at high pH, in the presence of Ca 2+ or Mg 2+ , while at pH 7.0, in the presence of EDTA, GSH does not increase the O 2 consumption of mitochondria

When central serotonin levels are depleted, these inhibitory pathways fail, causing the "volume" of pain signals to be turned up to an excruciating levela phenomenon known as central sensitization
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25 , 838855 e815 (2017)
