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Z.JiangS.ZhangL.YuZ

The protective effect of UA on dopaminergic neurons was also confirmed in rodent models of PD [171]

This finding underscores the potential therapeutic value of inhibiting the mtROS/HIF-2 signaling pathway and ameliorating the hypoxic microenvironment to attenuate the detrimental effects of CXCL4 in MS and other CXCL4-driven inflammatory disorders
In short, it has been deduced that the antagonistic role of GSH in cancer progression is mediated by the oxidative inactivation of PKC isozymes
