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Lack of insulin receptor signaling in Leprechaunism may result in the rare event of an alive but severely small for gestational age baby that will only survive if treated with recombinant-IGF-1 to substitute inulin receptor signaling with IGF1R signaling via their common intracellular pathways

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It occurs naturally in the body and is involved in the transport of hydrogen and plays an important role as an antioxidant