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Description
Endoscopic Sleeve Gastroplasty, also known as ESG, is a non-surgical endoscopic weight loss procedure

produced similar neuroendocrine effects in mice than those caused by an acute fast, including suppression of thyroid and reproductive axes, increased glucocorticoid secretion, increase in hypothalamic AgRP and NPY expression and decreased POMC expression 1, 15

Subsequent development toward clinical use has been minimal, and the compound has not entered FDA-approved status for any indication

Research investigates its effects on cellular energy metabolism and adipocyte function in experimental models
