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Overall, the application of these neurons successfully models key pathological attributes that are characteristic of AD, including aggregation of amyloid beta, modified production of A40 or A42, hyperphosphorylation of TAU, reduction in synapses and their plasticity as well as amplification of oxidative stress [44]

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Garcia-Segura S, Del Rey J, Closa L, Garcia-Martnez I, Hobeich C, Castel AB, Vidal F, Benet J, Ribas-Maynou J, Oliver-Bonet M (2022) Seminal Microbiota of Idiopathic Infertile Patients and Its Relationship With Sperm DNA Integrity

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