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In general MetS continues to be a clustering of symptoms that seem to play a major role as CVD and T2D risk factors, raising the necessity of encouraging these patients to pursue lifestyle changes

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Predrag Sikiric and colleagues at the University of Zagreb, Croatia in 1993

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In human studies, NOD2 polymorphism has also been connected to Crohns disease (CD) (47)

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Aside from this, the disease itself may lead to anemia, renal dysfunction, and hyperviscosity, exacerbating these cardiovascular symptoms

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