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In our EBOV polymerase structure, the positions of the priming and intrusion loops and the supporting helix are similar to those of other nsNSV polymerase structures in the elongation state 36 , suggesting that the structure we obtained also belongs to the elongation state

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A clinical case series reported that DSIP administration during opioid detoxification reduced withdrawal severity and improved sleep quality in patients undergoing tapering protocols (Iyer et al., Neurosci Biobehav Rev, 1988

Additionally, as the closely interrelated increased pressure in the three body cavities was rapidly transmitted through the venous system [23] (and thereby, the venous system can be seen as a therapy target [14,15,16,17,18,19,20,21,22,23]), the brain swelling and lesions and increased pressure in the superior sagittal sinus may induce a comparable deadly syndrome [20]