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Description
Luk, E., Carroll, M., Baker, M

Thus, it is possible to reach succinyl-CoA by other routes, not just from glutamine, but also from valine, methionine, and threonine

doi: 10.3389/fmicb.2012.00071 288 SimonisA.HeblingS.GulbinsE.Schneider-SchauliesS.Schubert-UnkmeirA

The ADC linker should be stable enough in the circulation to maintain the ADC drug concentration in the blood circulation and not be released before the cytotoxic drug reaches the target, thereby causing minimal off-target effects and improving the safety of the ADC drug
