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PMID: 27517151 Citations are provided for research reference

Under the ICH M7(R2) guideline, the mutagenic potential of impurities is initially assessed using two complementary in silico (Q)SAR models, i.e., one expert rule-based and one statistical-based model to predict the outcome of bacterial reverse mutation tests, such as the Ames test

Severely compromised skin barriers

If the genes governing this regeneration become less accessible due to age-related chromatin condensation, gut function suffers