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A 2011 systematic review of clinical data suggested that citicoline could hasten the resorption of cerebral edema and improve the recovery of consciousness and neurologic disorders in severe TBI cases (classified by Glasgow Coma Scale [GCS] scores of 8) (5)

Natarajan, R., Forrester, L., Chiaia, N

Defects in the OCTN2 gene cause primary carnitine deficiency, further emphasizing the strategic position of OCTN2 in maintaining carnitine homeostasis [165]

Free L-carnitine, absorbed from dietary intake or synthesized in liver and kidney, reaches the blood stream and the extracellular fluid
