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You never know what seemingly small, but ultimately significant, course of action may make a big difference in the end
Mechanisms of MDR Mechanisms of MDR can be divided into seven categories: (1) increasing drug efflux by membrane transporters, with ATP-binding cassette (ABC) transporters as the main transporters [30]
Furthermore, GTP cyclohydrolase 1 (GCH1) can suppress ferroptosis via the generation of the radical-trapping antioxidant tetrahydrobiopterin (BH4) (56)
MIA treatment of chondrocytes simulates the acute damage, which may not fully recapitulate the chronic progression of OA
