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By secreting capsular components that stimulate microglia to produce IL-8, a potent neutrophil chemoattractant, cryptococcal cells paradoxically impair neutrophil recruitment

Add to that our increasingly fine-tuned understanding of some of the regulated ROS generating systems that produce a significant fraction of the oxidants to be sensed, and it is clear that we CAN begin to construct models for these complex biological networks, but that continued research will be required in order to better understand the redox chemistry underlying vital cell processes

Some factories focus on large-scale production for established brands, while others specialize in helping new entrepreneurs bring their first products to market

2016 Dec;26(12):168192