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The unique microenvironmental and intrinsic cell properties of brain tumors have made them practically resistant to majority of conventional and cutting-edged therapies [3]

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The use of those agents is associated with many advantages, such as anti-toxic properties (Mirzaei et al., 2017)

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uri-Blake, B

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Temsirolimus Temsirolimus, an analog of everolimus, inhibits RPE and endothelial cell proliferation and migration, and decreases VEGF and PDGF expression [231], which can be used to alleviate AMD and DR

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