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Moreover, even in mice that are not exposed to high fat diet, deletion of a negative regulator of NFkB, A20, induces hypothalamic microgliosis and increases food intake and weight gain (Valdearcos et al
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The Liver--Cell Axis in Health and in Disease

Gut colonization with methanogenic archaea reduced plasma TMAO levels and attenuated the burden of AS, with decreased area and fat content in the atherosclerotic plaques, in Apo E / mice fed a TMA-supplemented or high choline diet (Ramezani et al., 2018)