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A hallmark of NDDs is the accumulation of toxic protein aggregates in the brain
10.1016/j.stem.2008.07.004 Cell Stem Cell 65 MiyataH.ToyodaY.TakadaT.HiragiT.KubotaY.ShigesawaR.et al (2022)
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Under normal conditions, magnesium sits inside the channel and physically blocks calcium
