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Research protocols explore combination approaches with other senolytic compounds such as dasatinib and quercetin, providing frameworks for studying multi-target senolytic strategies and understanding synergistic effects in various experimental models and disease research applications

Therefore, due to the loss of inhibitory control of GDH by mutations in GLUD1 , insulin was secreted excessively under basal conditions as well as after protein meals, triggering hyperinsulinemia and hypoglycemia [15]

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LOX enzymes, which catalyze the dioxygenation of polyenoic fatty acids to form hydroperoxides, are another source of lipid radicals