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doi: 10.1111/pme.12081

Conclusion Molecular mechanisms underlying the resistance of pituitary tumor to pharmacological treatment with DA and SS analogs might involve different steps that from the receptor activation by agonist lead to the final biological responses in terms of hormone secretion inhibition as well as tumor shrinkage

This defined stoichiometry means each molecule delivers exactly one copper ion, allowing researchers to calculate precise copper concentrations in their experimental systems a critical consideration since copper is biologically active at nanomolar concentrations but cytotoxic at micromolar levels

Journal of Cosmetic Dermatology, 20(12), 37593781