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glutathione peroxidase dna damage 2 - an overview Glutathione and the Cofactors
Description
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Since GSH oxidation involves hydrogen peroxide reduction, any issue in GSH metabolism is apt to cause an overabundance of oxygen radicals
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Meanwhile, the JAK-STAT-driven inflammatory mediators IL-6 and IFN- upregulate hepcidin, suppressing iron export and causing intracellular iron accumulation
